A	B	C
1	Main
2		Brand	fka CTX001
3		Generic	exagamglogene autotemcel
4		Indication	Sickle Cell Anemia, Beta-Thalassemia
5		MOA	HbF
6		Economics	60/40 VRTX
7		Clinical Trials
8			CLIMB-111
9
10			CLIMB-121
11			42/44 with TDT were transfusion-free, 2 had 75% and 89% reduction in transfusions
12			31/31 free of VOCs
13
14			CLIMB-131 open-label for 111, 121, 141, 151
15
16			Phase III "CLIMB-141" TDT
17
18			Phase III "CLIMB-151" SCD