A	B	C	D	E
1	Main
2		Brand Name	Seroquel, XR
3		Indication	schizophrenia, bipolar disorder
4		Mechanism	atypical antipsychotic
5		Safety	Less EPS side effects relative to class, more favorable weight gain vs Zyprexa but equal to Risperdal.
6		Price	7% increase 1/2006
7		Competition	Zyprexa, Abilify, Risperidone/Invega
8		Follow-on	Seroquel SR will be qd dosing, effect as early as Day 2 and with faster titration.
9		IP	September 2011 expiry. Pediatric extension applicable.
10			June 4 2008 summary judgment hearing with Teva? August 20 2008 30-month stay expiry. Summary judgment granted and no inequitable conduct found.
11			Anchen filed P4 in March 2010.
12			Sues Osmotica and Torrent 8/2010.
13		Clinical Studies	BOLDER I and BOLDER II bipolar studies (n=1045). PDUFA 10/30.
14			MDD, GAD
15
16			Seroquel SR data at ECP.
17
18
19		Rx		TRx	NRx
20			6/1/2007	287913	141565
21			5/25/2007	297841	152431
22			6/1/2006	264850	130220