| A | B | C | |
|---|---|---|---|
| 1 | Main | ||
| 2 | Brand Name | Kevzara | |
| 3 | Generic Name | REGN88 | |
| 4 | Mechanism | fully human monoclonal antibody against IL-R6 | |
| 5 | Indication | RA, ankylosing spondylitis | |
| 6 | Competition | Actemra (IL-6R antibody tocilizumab fr DNA), TNFs, etc | |
| 7 | Economics | Sanofi | |
| 8 | Administration | ||
| 9 | Clinical Trials | ||
| 10 | Phase 2/3 in RA -- initial results expected mid-2011 | ||
| 11 | |||
| 12 | |||
| 13 | Phase 2 in ankylosing spondylitis -- initial results expected mid-2011 | ||
| 14 | |||
| 15 | |||
| 16 | Phase 1 data from EULAR 2010 and ACR 2010 | ||
| 17 | dose-related reductions in biomarkers of inflammation |