ABCD
1Main
2Brand NameLyrica
3Generic Namepregabalin
4MechanismGABA mimetic that modulates voltage-gated calcium channels in the CNS.
5IndicationNeuropathic pain associated with diabetic peripheral neuropathy, post-herpetic neuralgia, adjunctive partial onset seizures, fibromyalgia.
6GAD received rec in EU on 1/29, non-approvable in the US in 2004
7Timeline6/27/2007: Receives approval for fibromyalgia.
8IP6197819 expires 12/30/18. COM-style patent issued to Northwestern University. Filed 1995, continued from 1992 and 1990 filings. Issued 2001.
95563175 issued 10/8/96, expires 10/8/13. 5-year HW?
10Rx
11NRXTRX
12
1311/13/200949634209947
1411/6/200952695220362
1510/30/200952148210793
1610/23/200952617207146
1710/16/200952309201328
1810/9/200957242208037
1910/2/200959496219471
209/25/200957651210721
2111/7/2008128829242130
228/10/2007104844175214
238/3/2007105008177479
247/27/2007100901168257
257/20/200799262167102
267/13/200798465162285
277/6/200785691155583
286/18/200793717162729
296/11/200782375148171
304/20/200787415151082
314/13/200784808147646
321/26/200783184140832
331/12/200785518147117
341/5/200775652139183
3512/29/200664517120643
3612/15/2006137766
3712/8/2006140308