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| Main | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| CHF | 1H03 | 2H03 | 1H04 | 2H04 | 1H04 | 2H04 | 1H05 | 2H05 | 1H06 | 2H06 | 1H07 | 2H07 | 1H08 | 2H08 | 1H09 | 2H09 | 1H10 | 2H10 | 1H11 | 2H11 | 1H12 | 2H12 | 1H13 | 2H13 | 1H14 | 2H14 | 1H15 | 2H15 | 1H16 | 2H16 | 1H17 | 2H17 | 1H18 | 2H18 | 1H19 | 2H19 | 1H20 | 2H20 | 1H21 | 2H21 | 1H22 | 2H22 | | | | | | Q104 | Q204 | Q304 | Q404 | Q105 | Q205 | Q305 | Q405 | Q106 | Q206 | Q306 | Q406 | Q107 | Q207 | Q307 | Q407 | Q108 | Q208 | Q308 | Q408 | Q109 | Q209 | Q309 | Q409 | Q110 | Q210 | Q310 | Q410 | Q111 | Q211 | Q311 | Q411 | Q112 | Q212 | Q312 | Q412 | Q113 | Q213 | Q313 | Q413 | Q114 | Q214 | Q314 | Q414 | Q115 | Q215 | Q315 | Q415 | Q116 | Q216 | Q316 | Q416 | Q117 | Q217 | Q317 | Q417 | Q118 | Q218 | Q318 | Q418 | Q119 | Q219 | Q319 | Q419 | Q120 | Q220 | Q320 | Q420 | Q121 | Q221 | Q321 | Q421 | Q122 | Q222 | Q322 | Q422 | Q123 | Q223 | Q323 | Q423 | | | | | | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | 2029 | 2030 | 2031 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Drugs | | | | | | | | | | | | | | | 19477 | 20063 | 18474 | 18584 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 5217.904642409034 | 5426.609786700125 | 5487.282308657465 | 5562.70765962469 | 6156 | 6507.728262602233 | 6761.271737397766 | 7867 | 7733 | 7837 | 8359.257867588683 | 9025.146521744966 | 7729 | 7696 | 9212 | 10011 | 8795 | 8902 | 9138 | 9972 | 9396 | 10081 | 10101 | 9962 | 8512 | 9659 | 9009 | 8663 | 8712 | 8103 | 7582 | 8397 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 9557 | 10001 | 10547 | 10511 | 11159 | 10082 | 9636 | 11562.100000000002 | 0 | 0 | 0 | 0 | | | | | | 17200 | 17703 | 19781 | 21694.504397391313 | 27292 | 32088.40438933365 | 31009 | 30761 | 39540 | 36911 | 32794 | 30432 | 31404 | 30229.620000000003 | 29747.1812 | 29677.626001999997 | 28642.10138276 | 27880.45760041781 | 23580.29338870334 | 44532 | 45041 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| United States | | | 2051 | 2470 | | | 2867 | 3747 | 4223 | 4902 | 5227 | 5187 | 4867 | 5594 | 7516 | 7289 | 7372 | 6699 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1982 | 2056 | 2167 | 2299 | 2603 | 2547 | 2680 | 2623 | 2564 | 3326 | 2468 | 2669 | 2925 | 3586 | 3930 | 3641 | 3648 | 3647 | 3725 | 3506 | 3193 | 3322 | 2963 | 2819 | 3119 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2866 | 3250 | 3382 | 4521 | 6614 | 9125 | 10414 | 10461 | 14805 | 14071 | 12223 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Chugai | | | | | | | 1807 | 1892 | 1684 | 1819 | 1674 | 1725 | 1452 | 1884 | 2184 | 2581 | 2061 | 2258 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 748 | 807 | 767 | 881 | 955 | 852 | 826 | 1066 | 862 | 822 | 841.7815970562415 | 1017.5078900940982 | 893 | 781 | 808 | 917 | 671 | 781 | 782 | 1102 | 1139 | 1045 | 1306 | 1275 | 988 | 1073 | 1076 | 1182 | 903 | 928 | 881 | 1105 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1000 | 1585 | 3156 | 3203 | 3699 | 3503 | 3399 | 3336 | 4765 | 4319 | 3817 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Diagnostics | | | | | | | 3970 | 4273 | 4272 | 4475 | 4559 | 4791 | 4747 | 4909 | 4902 | 5153 | 5250 | 5165 | 4856 | 4881 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2235 | 2091 | 2181 | 2143 | 2332 | 2216 | 2343 | 2264 | 2527 | 2287 | 2460 | 2365 | 2544 | 2361 | 2541 | 2463 | 2690 | 2518 | 2732 | 2482 | 2683 | 2408 | 2448 | 2239 | 2642 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4330 | | 4263 | 4455 | 5286 | 4662 | 3900 | 4410.45 | | | | | | | | | | 2866 | 3250 | 3382 | 4522 | 6614 | 8747 | 9350 | 9656 | 10055 | 10415 | 9737 | | | | | | 12079 | 12879 | 12950 | 13791 | 17760 | 18258.45 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| International | | | | | | | | | | | | | | | | | 4909 | 4292 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2238 | 2495 | 2414 | 2176 | 2116 | 2278 | 2122 | 1971 | 2162 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2238 | 9201 | 8533 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Western Europe | | | | | | | 7978 | 8977 | 9670 | 10996 | 11367 | 11603 | 10938 | 11226 | 9404 | 7784 | 5044 | 4423 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 3546 | 3494 | 3483 | 3447 | 3859 | 4119 | 4191 | 4786 | 4821 | 4849 | 5017.1291249999995 | 5572.7543856047305 | 5702 | 5665 | 5425 | 6178 | 4571 | 5440 | 5485 | 5741 | 4491 | 4913 | 4983 | 2801 | 2597 | 2447 | 2251 | 2172 | 2209 | 2090 | 1911 | 2011 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 13334 | 12868 | 13243 | 13970 | 16955 | 20666 | 22970 | 22164 | 17188 | 9467 | 8221 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Ocrevus | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1226 | 1212 | 1283 | 1334 | 1449 | 1461 | 1517 | 1467.4 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4326 | 5055 | 5894.4 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Perjeta | | | | | | | | | | | | | | | | | | | | | | | | | 388 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 30 | 50 | 58 | 78 | 140 | 178 | 210 | | | | | | | | | | | | | | | | | | | | | | | | | | | 988 | 980 | 1006 | 981 | 993 | 1068 | 1029 | 1079.1000000000001 | | | | | | | | | | | | | | | | | | | | | 30 | 326 | 489 | 586.8 | 645.48 | 710.0280000000001 | 781.0308000000002 | | 3883 | 3955 | 4169.1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Hemlibra | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 661 | 732 | 779 | 850 | 853 | 973 | 952 | 935.0000000000001 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2190 | 3022 | 3713 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tecentriq | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 775 | 824 | 878 | 838 | 825 | 933 | 934 | 921.8000000000001 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2738 | 3315 | 3613.8 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| RoActemra | | | | | | | | | | | | | | | | | 155 | 242 | 277 | 341 | | | | | 568 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 66 | 89 | 107 | 135 | 129 | 148 | 156 | 185 | 184 | 201 | 216 | 241 | 238 | 258 | 267 | 274 | 273 | 295 | | | | | | | | | | | | | | | | | | | | | | | | | | | 779 | 863 | 1048 | 872 | 792 | 663 | 584 | 959.2 | | | | | | | | | | | | | | | | | | | 397 | 618 | 842 | 1037 | 1140.7 | 1254.7700000000002 | 1380.2470000000003 | 1518.2717000000005 | 1670.0988700000007 | 1837.1087570000009 | 2858 | 3562 | 2998.2 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Avastin | | | | | | | 607 | 1058 | 1389 | 1573 | 1909 | 2197 | 2351 | 2856 | 3090 | 3132 | 3393 | 3068 | 2726 | 2566 | 2726 | 2694.3 | | | 3097 | | | | | | | | | | | | | | | | | | | | | | | 48 | 169 | 235 | 238 | 260 | 347 | 486 | 572 | 676 | 713 | 741 | 832 | 923 | 986 | 1062 | 1135 | 1131 | 1220 | 1351 | 1505 | 1485 | 1605 | 1594 | 1538 | 1666 | 1727 | 1608 | 1460 | 1417 | 1309 | 1216 | 1350 | 1385 | 1420 | 1504 | 1455 | 1527 | 1566 | 1617 | 1544 | 1565 | 1532 | | | | | | | | | | | | | | | | | | | | | | | | | | | 863 | 782 | 745 | 666 | 581 | 561 | 510 | 732.6 | | | | | | | | | | 0 | 0 | 0 | 690 | 1665 | 2962 | 4106 | 5207 | 6222 | 6461 | 5292 | 5764 | 6254 | 6316.54 | 6379.7054 | 6443.5024539999995 | 6507.93747854 | 6573.0168533254 | 6507.286684792146 | 4992 | 3056 | 2384.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Mabthera/Rituxan | | | | | | | 1944 | 2210 | 2348 | 2491 | 2704 | 2812 | 2867 | 3056 | 3098 | 2989 | 3301 | 3055 | 3056 | 2949 | 3178.2400000000002 | 3066.96 | | | 3360 | | | | | | | | | | | | | | | | | | | | | | | 782 | 842 | 880 | 874 | 929 | 1015 | 1057 | 1153 | 1146 | 1202 | 1177 | 1314 | 1309 | 1395 | 1380 | 1432 | 1407 | 1460 | 1472 | 1584 | 1481 | 1617 | 1508 | 1481 | 1606 | 1695 | 1520 | 1535 | 1556 | 1500 | 1361 | 1588 | 1605 | 1710 | 1683 | 1709 | 1696 | 1705 | 1805 | 1745 | 1667 | 1693 | | | | | | | | | | | | | | | | | | | | | | | | | | | 705 | 674 | 589 | 597 | 564 | 553 | 479 | 656.7 | | | | | | | | | | 1721 | 2402 | 2775 | 3378 | 4154 | 4839 | 5516 | 5923 | 6087 | 6356 | 6005 | 6707 | 6951 | 7020.51 | 7090.7151 | 7161.622251000001 | 7090.006028490001 | 7019.105968205101 | 6948.91490852305 | 4223 | 2565 | 2252.7 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Herceptin | | | | | | | 851 | 1295 | 1813 | 2114 | 2382 | 2470 | 2474 | 2618 | 2645 | 2621 | 2806 | 2623 | 2716 | 2537 | 2824.64 | 2638.48 | | | 3082 | | | | | | | | | | | | | | | | | | | | | | | 328 | 356 | 373 | 377.70765962469017 | 391 | 460 | 591 | 704 | 861 | 952 | 1009 | 1105 | 1168 | 1214 | 1209 | 1261 | 1225 | 1249 | 1295 | 1323 | 1307 | 1338 | 1327 | 1294 | 1417 | 1389 | 1357 | 1266 | 1386 | 1330 | 1189 | 1348 | 1428 | 1523 | 1481 | 1457 | 1572 | 1510 | 1512 | 1485 | 1526 | 1556 | | | | | | | | | | | | | | | | | | | | | | | | | | | 755 | 641 | 665 | 633 | 607 | 572 | 493 | 696.3000000000001 | | | | | | | | | | 806 | 1007 | 1177 | 1434.7076596246902 | 2146 | 3927 | 4852 | 5092 | 5266 | 5429 | 5253 | 5889 | 6079 | 6139.79 | 6201.1879 | 6263.199779 | 5636.8798011 | 5073.19182099 | 4565.872638891001 | 3732 | 2694 | 2368.3 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Kadcyla | | | | | | | | | | | | | | | | | | | | | | | | | 227 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 65 | 73 | 78 | 102 | 125 | | | | | | | | | | | | | | | | | | | | | | | | | | | 478 | 481 | 501 | 522 | 511 | 563 | 516 | 574.2 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1745 | 1982 | 2164.2 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Ronapreve | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 166 | 429 | 489 | 546 | 587 | 22 | 22 | 600.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 1630 | 1231.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xolair | | | | | | | 181 | 227 | 257 | 280 | 284 | 283 | 259 | 301 | 313 | 307 | 324 | 317 | 300 | 303 | | | | | 437 | | | | | | | | | | | | | | | | | | | | | | | 38 | 55 | 68 | 73 | 81 | 100 | 104 | 123 | 124 | 133 | 135 | 145 | 136 | 148 | 145 | 138 | 125 | 134 | 145 | 156 | 152 | 161 | 157 | 150 | 148 | 176 | 167 | 150 | 149 | 151 | 146 | 157 | 164 | 181 | 185 | 175 | 185 | 201 | 204 | 200 | 205 | 232 | | | | | | | | | | | | | | | | | | | | | | | | | | | 409 | 478 | 529 | 526 | 456 | 569 | 600 | 578.6 | | | | | | | | | | 0 | 0 | 33 | 234 | 408 | 537 | 567 | 560 | 620 | 641 | 603 | 705 | 790 | 797.9 | 805.879 | 813.9377900000001 | 822.0771679000001 | 830.2979395790001 | 838.60091897479 | 1904 | 1942 | 2203.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Alecensa | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 298 | 333 | 357 | 368 | 361 | 384 | 382 | 404.8 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1160 | 1356 | 1531.8 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Lucentis | | | | | | | | | 13 | 465 | 524 | 467 | 440 | 520 | 573 | 625 | 697 | 761 | 769 | 754 | | | | | 828 | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13 | 192 | 273 | 263 | 261 | 239 | 228 | 215 | 225 | 246 | 274 | 279 | 294 | 296 | 329 | 327 | 370 | 384 | 377 | 392 | 377 | 359 | 395 | 385 | 360 | 368 | 368 | 393 | 427 | 431 | 438 | 407 | 421 | | | | | | | | | | | | | | | | | | | | | | | | | | | 337 | 328 | 352 | 336 | 256 | 316 | 228 | 369.6 | | | | | | | | | | 0 | 0 | 0 | 0 | 0 | 478 | 991 | 960 | 1198 | 1458 | 1523 | 1481 | 1689 | 1705.89 | 1722.9489 | 1740.1783890000002 | 1757.58017289 | 1775.1559746189 | 1792.907534365089 | 1444 | 1353 | 1169.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Activase/TNKase | | | | | | | | 310 | 178 | 184 | 202 | 180 | 164 | 178 | 226 | 229 | 227 | 233 | 231 | 222 | | | | | 359 | | | | | | | | | | | | | | | | | | | | | | | 63 | 72 | 76 | 67 | 67 | 72 | 84 | 87 | 88 | 90 | 89 | 95 | 96 | 106 | 92 | 88 | 83 | 81 | 81 | 97 | 126 | 100 | 107 | 122 | 110 | 117 | 119 | 114 | 122 | 109 | 100 | 122 | 140 | 145 | 152 | 147 | 190 | 151 | 173 | 169 | 181 | 178 | | | | | | | | | | | | | | | | | | | | | | | | | | | 304 | 294 | 323 | 391 | 247 | 312 | 322 | 430.1 | | | | | | | | | | 371 | 322 | 278 | 278 | 310 | 362 | 382 | 342 | 455 | 460 | 453 | 584 | 683 | 717.15 | 753.0075 | 790.6578750000001 | 830.1907687500002 | 871.7003071875002 | | 1321 | 1312 | 1311.1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Esbriet | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 256 | 270 | 263 | 250 | 241 | 216 | 133 | 275 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1108 | 1039 | 865 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Evrysdi | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 80 | 163 | 153 | 206 | 226 | 274 | 293 | 226.60000000000002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 55 | 602 | 1019.6 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Gazyva | | | | | | | | | | | | | | | | | | | | | | | | | 18 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 155 | 169 | 177 | 177 | 165 | 184 | 190 | 194.70000000000002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 632 | 678 | 733.7 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Phesgo | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 29 | 67 | 117 | 127 | 146 | 179 | 201 | 139.70000000000002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 23 | 340 | 665.7 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Pulmozyme | | | | | | | 186 | 207 | 212 | 224 | 231 | 252 | 237 | 259 | 248 | 253 | 264 | 249 | 247 | 245 | | | | | 278 | | | | | | | | | | | | | | | | | | | | | | | 84 | 81.79673776662484 | 86 | 86 | 89 | 97 | 100 | 107 | 109 | 103 | 108 | 116 | 111 | 120 | 124 | 128 | 117 | 120 | 120 | 139 | 120 | 128 | 125 | 128 | 135 | 129 | 121 | 128 | 131 | 116 | 111 | 134 | 128 | 129 | 139 | 141 | 140 | 138 | 134 | 160 | 138 | 140 | | | | | | | | | | | | | | | | | | | | | | | | | | | 139 | 137 | 138 | 152 | 136 | 143 | 135 | 167.20000000000002 | | | | | | | | | | 319 | 320 | 328 | 337.79673776662486 | 393 | 436 | 483 | 496 | 501 | 513 | 492 | 537 | 572 | 600.6 | 630.63 | 662.1615 | 695.269575 | 730.03305375 | 657.029748375 | 642 | 566 | 581.2 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| CellCept | | | | | | | 800 | 905 | 891 | 951 | 979 | 1033 | 1010 | 1089 | 927 | 649 | 702 | 588 | 538 | 453 | | | | | 413 | | | | | | | | | | | | | | | | | | | | | | | 369 | 350 | 337 | 347 | 370 | 430 | 441 | 464 | 454 | 437 | 466 | 485 | 476 | 503 | 485 | 548 | 487 | 523 | 513 | 576 | 517 | 410 | 362 | 287 | 357 | 345 | 299 | 289 | 280 | 258 | 232 | 221 | 220 | 234 | 230 | 225 | 229 | 236 | 216 | 193 | 215 | 198 | | | | | | | | | | | | | | | | | | | | | | | | | | | 154 | 144 | 155 | 139 | 134 | 136 | 116 | 152.9 | | | | | | | | | | 1056 | 1173 | 1335 | 1403 | 1705 | 1842 | 2012 | 2099 | 1576 | 1290 | 991 | 909 | 874 | 524.4 | 314.64 | 188.784 | 113.2704 | 67.96224 | 40.77734399999999 | 606 | 592 | 538.9 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Polivy | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 81 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 169 | 247 | 81 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Erivedge | | | | | | | | | | | | | | | | | | | | | | | | | 57 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 63 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 278 | 269 | 63 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Enspryng | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 41 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Vabysmo | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 21 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Rozlytrek | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 16 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Cotellic | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 12 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Gavreto | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 5 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xofluza | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Susivmo | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| NeoRecormon/Epogin | | | | | | | 1086 | 1166 | 1100 | 1127 | 1066 | 1028 | 892 | 882 | 789 | 771 | 677 | 608 | 493 | 403 | | | | | 231 | | | | | | | | | | | | | | | | | | | | | | | 489 | 531 | 528 | 534 | 516 | 570 | 564 | 602 | 535 | 565 | 535 | 592 | 522 | 544 | 518 | 510 | 442 | 450 | 427 | 455 | 378 | 411 | 391 | 380 | 339 | 338 | 312 | 296 | 246 | 247 | 197 | 206 | 171 | 180 | 170 | 153 | 131 | 138 | 131 | 120 | 112 | 119 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 746 | 1192 | 2051 | 2082 | 2252 | 2227 | 2094 | 1774 | 1560 | 1285 | 896 | 674 | 520 | 514.8 | 509.65199999999993 | 504.55547999999993 | 499.50992519999994 | 494.51482594799995 | 489.56967768851996 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Pegasys | | | | | | | 680 | 723 | 724 | 743 | 807 | 830 | 785 | 850 | 842 | 813 | 869 | 776 | 695 | 743 | | | | | 582 | | | | | | | | | | | | | | | | | | | | | | | 289 | 295 | 296 | 299 | 325 | 355 | 350 | 373 | 350 | 374 | 350 | 393 | 400 | 407 | 383 | 447 | 369 | 416 | 405 | 445 | 393 | 449 | 438 | 375 | 441 | 428 | 384 | 392 | 346 | 349 | 356 | 387 | 444 | 459 | 374 | 372 | 375 | 349 | 303 | 285 | 287 | 295 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 94 | 719 | 1179 | 1403 | 1467 | 1637 | 1635 | 1655 | 1645 | 1438 | 1649 | 1312 | 1049.6000000000001 | 839.6800000000002 | 671.7440000000001 | 537.3952000000002 | 429.91616000000016 | 343.9329280000002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xeloda | | | | | | | 355 | 441 | 472 | 499 | 549 | 602 | 573 | 638 | 626 | 634 | 732 | 694 | 668 | 686 | | | | | 474 | | | | | | | | | | | | | | | | | | | | | | | 115 | 128 | 145 | 146 | 165 | 190 | 213 | 228 | 238 | 234 | 239 | 260 | 267 | 282 | 290 | 312 | 281 | 292 | 307 | 331 | 296 | 330 | 326 | 308 | 352 | 380 | 361 | 333 | 342 | 326 | 333 | 353 | 382 | 381 | 386 | 374 | 383 | 388 | 393 | 345 | 293 | 181 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 260 | 444 | 515 | 534 | 796 | 971 | 1151 | 1211 | 1260 | 1426 | 1354 | 1523 | 1509 | 754.5 | 377.25 | 188.625 | 94.3125 | 47.15625 | 23.578125 | 301 | 194 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tarceva | | | | | | | 145 | 242 | 367 | 446 | 503 | 559 | 587 | 628 | 643 | 661 | 674 | 651 | 614 | 637 | | | | | 651 | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 17 | 57 | 88 | 101 | 141 | 172 | 195 | 211 | 235 | 243 | 260 | 271 | 288 | 286 | 301 | 298 | 330 | 320 | 323 | 319 | 342 | 326 | 348 | 331 | 320 | 317 | 297 | 307 | 330 | 337 | 329 | 323 | 325 | 336 | 355 | 327 | 321 | 304 | 347 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 17 | 387 | 813 | 1062 | 1215 | 1304 | 1325 | 1251 | 1314 | 1339 | 1352.39 | 1365.9139 | 1379.573039 | 1393.3687693900001 | 1407.3024570839002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Bonviva/Boniva | | | | | | | 21 | 65 | 167 | 321 | 374 | 513 | 507 | 601 | 525 | 533 | 544 | 469 | 394 | 302 | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 0 | 0 | 21 | 14 | 51 | 75 | 92 | 142 | 179 | 170 | 204 | 230 | 283 | 241 | 266 | 268 | 333 | 249 | 276 | 255 | 278 | 277 | 267 | 246 | 223 | 212 | 182 | 157 | 145 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 0 | 86 | 488 | 887 | 1108 | 1058 | 1013 | 696 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tamiflu | | | | | | | 580 | 978 | 961 | 1666 | 1316 | 769 | 327 | 282 | 1010 | 2190 | 710 | 163 | 262 | 97 | | | | | 372 | | | | | | | | | | | | | | | | | | | | | | | 108 | 19 | 110 | 93 | 424 | 156 | 279 | 699 | 601 | 360 | 669 | 997 | 865 | 451 | 257 | 512 | 278 | 49 | 101 | 181 | 401 | 609 | 994 | 1196 | 517 | 193 | 98 | 65 | 252 | 10 | 39 | 58 | 187 | 34 | 20 | 319 | 335 | 45 | 34 | 221 | 344 | 28 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 110 | 175 | 431 | 330 | 1558 | 2627 | 2085 | 609 | 3200 | 873 | 359 | 560 | 635 | 654.0500000000001 | 673.6715 | 693.881645 | 346.9408225 | 173.47041125 | 86.735205625 | 272 | 58 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Valcyte/Cymevene | | | | | | | 185 | 209 | 223 | 265 | 261 | 281 | 261 | 292 | 274 | 290 | 296 | 309 | 282 | 287 | | | | | 353 | | | | | | | | | | | | | | | | | | | | | | | 86 | 79 | 81 | 83 | 86 | 99 | 100 | 109 | 110 | 113 | 126 | 139 | 124 | 137 | 137 | 144 | 128 | 136 | 143 | 149 | 131 | 143 | 148 | 142 | 149 | 147 | 157 | 152 | 145 | 137 | 143 | 144 | 153 | 154 | 171 | 160 | 166 | 167 | 166 | 194 | 177 | 176 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 292 | 296 | 281 | 329 | 394 | 488 | 542 | 556 | 564 | 605 | 569 | 638 | 693 | 346.5 | 173.25 | 86.625 | 43.3125 | 21.65625 | 10.828125 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Nutropin | | | | | | | 232 | 244 | 244 | 250 | 239 | 231 | 195 | 218 | 211 | 189 | 193 | 212 | 169 | 148 | | | | | | | | | | | | | | | | | | | | | | | | | | | | 109 | 116 | 110 | 114 | 110 | 122 | 116 | 128 | 118 | 126 | 118 | 132 | 117 | 122 | 118 | 113 | 97 | 98 | 106 | 112 | 104 | 107 | 100 | 89 | 91 | 102 | 117 | 95 | 87 | 82 | 73 | 75 | 77 | 77 | 77 | 73 | 73 | 71 | 69 | 61 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 435 | 477 | 442 | 449 | 476 | 494 | 470 | 413 | 400 | 405 | 317 | 304 | 274 | 287.7 | 302.085 | 317.18925 | 333.0487125 | 349.70114812500003 | 314.7310333125 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Neutrogin | | | | | | | 169 | 195 | 188 | 191 | 195 | 210 | 192 | 212 | 188 | 197 | 167 | 164 | 135 | 143 | | | | | | | | | | | | | | | | | | | | | | | | | | | | 76 | 80 | 81 | 88 | 80 | 89 | 97 | 98 | 93 | 95 | 91 | 100 | 96 | 99 | 100 | 110 | 95 | 97 | 98 | 114 | 90 | 98 | 101 | 96 | 81 | 86 | 82 | 82 | 61 | 74 | 65 | 78 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 315 | 325 | 364 | 379 | 405 | 404 | 385 | 331 | 278 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Madopar | | | | | | | | | | | | | 154 | 157 | 140 | 146 | 0 | 77 | 150 | 144 | | | | | 135 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 75 | 77 | 76 | 83 | 74 | 80 | 77 | 80 | 68 | 72 | 71 | 75 | | | | 77 | 75 | 75 | 72 | 72 | 75 | 82 | 78 | 75 | 80 | 78 | 77 | 78 | 59 | 76 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 311 | 311 | 286 | | 294 | 310 | 313 | 328.65000000000003 | 345.08250000000004 | 362.3366250000001 | 380.4534562500001 | 399.47612906250015 | 359.52851615625013 | 361 | 394 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Mircera | | | | | | | | | | | | | | | | | | | 138 | 206 | | | | | 203 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 70 | 70 | 68 | 99 | 107 | 90 | 87 | 96 | 111 | 94 | 106 | 107 | 118 | 103 | 100 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 344 | 384 | 425 | 429.25 | 433.5425 | 437.877925 | 442.25670425 | 446.6792712925 | | 470 | 435 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xenical | | | | | | | 312 | 323 | 363 | 330 | 339 | 293 | 264 | 238 | 209 | 188 | 183 | 154 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 146 | 165 | 145 | 137 | 147 | 165 | 162 | 161 | 181 | 182 | 160 | 170 | 163 | 176 | 151 | 142 | 136 | 128 | 126 | 112 | 103 | 106 | 98 | 90 | 91 | 92 | 76 | 78 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 963 | 763 | 618 | 593 | 635 | 693 | 632 | 502 | 397 | 337 | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Kytril | | | | | | | 235 | 265 | 254 | 244 | 205 | 220 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 109 | 111 | 114 | 123 | 105 | 130 | 130 | 135 | 130 | 124 | 127 | 117 | 105 | 100 | 110 | 110 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 437 | 451 | 437 | 457 | 500 | 498 | 425 | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Fuzeon | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 31 | 47 | 43 | 47 | 50 | 66 | 62 | 81 | 72 | 71 | 78 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 49 | 168 | 259 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Raptiva | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 7.904642409033876 | 16.813048933500628 | 23.282308657465496 | 22 | 28 | 31 | 28 | 30 | 31 | 31 | 32 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 3 | 70 | 117 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Dilatrend | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 104 | 96 | 86 | 75 | 83 | 84 | 79 | 80 | 81 | 78 | 75 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 289 | 329 | 392 | 361 | 326 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Evista | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 17 | 6 | 15 | 16 | 25 | 28 | 35 | 27 | 37 | 37 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 38 | 104 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Renagel | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 11 | 11 | 11 | 12 | 11 | 15 | 15 | 16 | 13 | 16 | 17 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 0 | 45 | 57 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Copegus | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 102 | 95 | 99 | 87 | 104 | 109 | 107 | 87 | 60 | 57 | 53 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0 | 223 | 383 | 407 | | | | | | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Zelboraf | | | | | | | | | | | | | | | | | | | | 31 | | | | | 155 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 32 | 60 | 65 | 77 | 84 | 87 | 89 | 94 | 79 | 76 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 234 | 354 | 389.40000000000003 | 428.3400000000001 | 471.17400000000015 | 518.2914000000002 | 570.1205400000002 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Rocephin | | | | | | | 614 | 313 | 216 | 200 | 204 | 195 | 176 | 168 | 164 | 143 | 165 | 146 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 369 | 305 | 307 | 321 | 330 | 284 | 152 | 161 | 110 | 106 | 96 | 104 | 100 | 104 | 95 | 100 | 91 | 85 | 76 | 92 | 77 | 87 | 73 | 70 | 82 | 83 | 77 | 69 | | | | | 73 | 60 | 65 | 68 | 68 | 70 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1755 | 1548 | 1375 | 1302 | 927 | 416 | 399 | 344 | 307 | 311 | | 266 | 138 | | | | | | | 252 | 244 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 300 | 400 | 500 | 600 | 600 | 600 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Other Pharma | | | | | | | | | | | | | | | 2736 | 425 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1354 | 1389 | 1247 | 1287 | 1332 | 1387.7282626022334 | 1301.2717373977657 | 1442 | 1278 | 1338 | 1286.2578675886843 | 1242.1465217449652 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 787 | | | | | | | | | | | | | 7640 | 6710 | 6004 | 5277 | 5462.999999999999 | 5144.404389333649 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Other | | | | | | | 4630 | 4141 | 4030 | 3927 | 3743 | 3798 | 2982 | 3067 | | | 2462 | 2285 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1759.910722056241 | 1801.2622756988276 | 1781 | 1810 | 1740 | 1899 | 1487 | 1492 | 1483 | 1584 | 1319 | 1417 | 1311 | 1192 | 1215 | 1247 | 1193 | 1092 | 1126 | 1106 | 1027 | 1127 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 7957 | 7541 | 6046 | 5239 | 4747 | 4386 | | | 0 | 0 | 0 | 0 | 0 | 0 | 2847 | 2584 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Revenue | 12810 | 14380 | 14526 | 14996 | | | 16622 | 18889 | 19849 | 22192 | 22827 | 23306 | 22004 | 23613 | 24006 | 25216 | 24636 | 22767 | 19439 | 18737 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 12262.168589644923 | 13158.408797443793 | 11726 | 11849 | 11476 | 12538 | 11082 | 11362 | 11503 | 12516 | 11757 | 12622 | 12564 | 12652 | 11030 | 12391 | 11491 | 11346 | 11120 | 10551 | 9821 | 11039 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 26066 | 27190 | 29522 | 35511 | 42041 | 46133 | 46463 | 49595 | 47326 | 42531 | 30432 | 46780 | 47462 | 47581 | 48149 | 45104 | 46273 | 51837 | 58323 | 62801 | 59812.54999999999 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Royalties | | | 790 | 860 | 710 | | 710 | 737 | 727 | 739 | 601 | 601 | 1136 | 1151 | 1116 | 984 | 878 | 816 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1570 | 1447 | 1466 | 1202 | 2287 | 2100 | 1694 | 1582 | 1582 | 1582 | 1582 | 1582 | 1582 | 1582 | 1582 | 1582 | 2020 | 3049 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Cost of Sales | 2895 | 3202 | 3193 | 3363 | 3760 | 3958 | 4348 | 4956 | 4934 | 5682 | 5629 | 8114 | 6532 | 7129 | 7100 | 7515 | 6870 | 6423 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 5984 | 6097 | 7718 | 9304 | 10616 | 13743 | 13661 | 14615 | 13293 | 11942 | 32014 | 48362 | 49044 | 49163 | 49731 | 46686 | 47855 | 53419 | 14567 | 18138 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Gross Profit | 9915 | 11178 | 11333 | 11633 | 10766 | 11038 | 12984 | 14670 | 15642 | 17249 | 17799 | 15793 | 16608 | 17635 | 18022 | 18685 | 18644 | 17160 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 20082 | 21093 | 21804 | 27654 | 32891 | 33592 | 35089 | 36707 | 35727 | 32171 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 45776 | 47712 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| M&D | 3658 | 4159 | 3983 | 4292 | 4000 | 4338 | 4409 | 5216 | 5208 | 5648 | 5552 | 3775 | 4371 | 4799 | 4567 | 4908 | 4546 | 4942 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 7859 | 7817 | 8338 | 9507 | 10856 | 9327 | 9170 | 9475 | 9488 | 8049 | 7968.51 | 7888.8249000000005 | 7809.936651000001 | 7731.8372844900005 | 7654.5189116451 | 7577.973722528649 | 7502.193985303363 | 7427.172045450329 | 9361 | 9444 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| G&A | 633 | 727 | 677 | 721 | 1059 | 1026 | 1145 | 1143 | 1072 | 1470 | 1237 | 1216 | 1089 | 1243 | 967 | 1208 | 871 | 2003 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1193 | 1360 | 2085 | 2309 | 2542 | 2453 | 2332 | 2175 | 2874 | 2342 | 2318.58 | 2295.3941999999997 | 2272.4402579999996 | 2249.7158554199996 | 2227.2186968657998 | 2204.946509897142 | 2182.8970447981706 | 2161.068074350189 | 2726 | 2663 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| R&D | 2173 | 2451 | 2333 | 2720 | 2361 | 2793 | 2559 | 3146 | 3063 | 3526 | 3635 | 4750 | 4107 | 4738 | 4518 | 5356 | 4471 | 5555 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4132 | 4624 | 5154 | 5705 | 6589 | 8385 | 8845 | 9874 | 10026 | 8326 | | | | | | | | | 12153 | 13708 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Unallocated Non-Cash Expenses | | | | | | | | | | | 1210 | 1390 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1210 | 2600 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Operating Expenses | | | | | | | | | | | 9214 | 8351 | 9567 | 10780 | 10052 | 11472 | 9888 | 12500 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 18777 | 17565 | 20347 | 21524 | 22388 | 18717 | 10287.09 | 10184.2191 | 10082.376909 | 9981.55313991 | 9881.737608510899 | 9782.920232425791 | 9685.091030101534 | 9588.240119800517 | 24240 | 25815 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Operating Profit | 2833 | 2960 | 3701 | 3249 | 3527 | 3239 | 4871 | 5165 | 6299 | 6605 | 8585 | 7442 | 7041 | 6855 | 7970 | 7213 | 8756 | 4660 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 5223 | 5793 | 6766 | 10133 | 14114 | 16027 | 14742 | 15183 | 13339 | 13454 | -10287.09 | -10184.2191 | -10082.376909 | -9981.55313991 | -9881.737608510899 | -9782.920232425791 | -9685.091030101534 | -9588.240119800517 | 21536 | 21897 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Financial Income | -75 | 122 | 131 | 106 | 213 | 156 | 241 | 437 | 902 | 927 | 979 | 826 | 684 | 684 | 484 | 308 | 302 | 252 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2000 | 47 | 369 | 1313 | 1829 | 1805 | 1123 | 792 | 554 | -1569 | -66.9 | -460.35162 | -864.84530736 | -1280.83975158168 | -1708.8106814583641 | -2149.251516477196 | -2602.67404293551 | -3069.6091157109176 | -564 | -751 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Financing Costs | -276 | -401 | -370 | -206 | -383 | -244 | -187 | -195 | 478 | 496 | 479 | 492 | 447 | 447 | 1035 | 1425 | 1508 | 1321 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -1165.161104477612 | -677 | -627 | 985 | 974 | 971 | 887 | 2460 | 2829 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Profit Before Taxes | 2464 | 2655 | 3435 | 3133 | 3330 | 3135 | 5299 | 5797 | 6723 | 7036 | 9085 | 7776 | 7278 | 7092 | 7419 | 6096 | 7550 | 3591 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 6020.838895522388 | 5119 | 6465 | 10461 | 14969 | 16861 | 14978 | 13515 | 11064 | 11885 | -10353.99 | -10644.57072 | -10947.22221636 | -11262.39289149168 | -11590.548289969263 | -11932.171748902987 | -12287.765073037044 | -12657.849235511436 | 20972 | 21146 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Income Taxes | -658 | -661 | -835 | -810 | -806 | -799 | 1095 | 1129 | 1701 | 1735 | 2115 | 1752 | 1861 | | 1678 | 1192 | 1800 | 520 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -1595 | -1319 | -1605 | 2284 | 3436 | 3867 | 3317 | 2870 | 2320 | 2341 | -2484.9575999999997 | -2554.6969728 | -2627.3333319263998 | -2702.974293958003 | -2781.731589592623 | -2863.7212197367166 | -2949.0636175288905 | -3037.8838165227444 | 3594 | 3075 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Profit After Taxes | 1806 | 1994 | 2600 | 2323 | 2524 | 2336 | 4204 | 4668 | 5022 | 5301 | 6970 | 6024 | 5417 | 7092 | 5741 | 4904 | 5750 | 3071 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4425.838895522388 | 3800 | 4860 | 8177 | 11533 | 12994 | 11661 | 10645 | 8744 | 9544 | -7869.0324 | -8089.873747199999 | -8319.8888844336 | -8559.418597533677 | -8808.81670037664 | -9068.45052916627 | -9338.701455508153 | -9619.965418988691 | 17378 | 18071 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Minority Interests | -185.5 | -243.5 | -274 | -306 | -262 | -276 | 444 | 499 | 572 | 719 | 943 | 733 | 912 | 912 | 578 | 148 | 97 | 128 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 34 | -429 | -538 | 943 | 1291 | 1676 | 1875 | 726 | 225 | 201 | | | | | | | | | 801 | 1033 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Net Income | 1620.5 | 1750.5 | 2326 | 2017 | 2262 | 2060 | 3760 | 4169 | 4450 | 4582 | 6027 | 5291 | 4505 | 6180 | 5163 | 4756 | 5653 | 2943 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4459.838895522388 | 3371 | 4322 | 7234 | 10242 | 11318 | 9786 | 9919 | 8519 | 9343 | -7869.0324 | -8089.873747199999 | -8319.8888844336 | -8559.418597533677 | -8808.81670037664 | -9068.45052916627 | -9338.701455508153 | -9619.965418988691 | 16577 | 17038 | 17208.38 | 17380.4638 | 17554.268438000003 | 17729.811122380004 | 17907.109233603805 | 18086.180325939844 | 18267.042129199242 | 18449.712550491236 | 18634.20967599615 | 18820.551772756113 | 19008.757290483674 | 19198.844863388513 | 19390.833312022398 | 19584.74164514262 | 19780.589061594048 | 19978.39495220999 | 20178.17890173209 | 20379.960690749413 | 20583.760297656907 | 20789.597900633475 | 20997.49387963981 | 21207.468818436206 | 21419.54350662057 | 21633.738941686774 | 21850.076331103643 | 22068.57709441468 | 22289.262865358825 | 22512.155494012415 | 22737.27704895254 | 22964.649819442064 | 23194.296317636483 | 23426.239280812846 | 23660.501673620976 | 23897.106690357185 | 24136.077757260755 | 24377.438534833364 | 24621.212920181697 | 24867.425049383513 | 25116.099299877347 | 25367.260292876123 | 25620.932895804883 | 25877.14222476293 | 26135.91364701056 | 26397.272783480665 | 26661.245511315472 | 26927.857966428626 | 27197.136546092912 | 27469.10791155384 | 27743.79899066938 | 28021.236980576075 | 28301.449350381838 | 28584.463843885656 | 28870.30848232451 | 29159.011567147758 | 29450.601682819237 | 29745.10769964743 | 30042.558776643906 | 30342.984364410346 | 30646.414208054448 | 30952.878350134994 | 31262.407133636345 | 31575.031204972707 | 31890.781517022435 | 32209.68933219266 | 32531.786225514585 | 32857.10408776973 | 33185.675128647425 | 33517.5318799339 | 33852.70719873324 | 34191.23427072057 | 34533.14661342777 | 34878.47807956205 | 35227.262860357674 | 35579.53548896125 | 35935.33084385086 | 36294.68415228937 |
| EPS | 1.9072573266926225 | 2.0566674424016758 | 2.727803738317757 | 2.3449074074074074 | 2.6395520047522396 | 2.4104238397498516 | 4.359103401990372 | 4.833271830557941 | 5.159045249696051 | 5.312077603170182 | 6.987318139307439 | 6.134046835088046 | 5.222808730310272 | 7.16469654901609 | 5.9856518256585876 | 5.5138020691133525 | 6.553726471130736 | 3.4119258808664 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 5.318432235922715 | 3.9639115250291037 | 5.0502424081454445 | 6.102642605743132 | 11.873919426379091 | 13.121364974395485 | 11.345262205286643 | 11.499453894771941 | 9.876383479137226 | 10.831676352339372 | -9.122852634365016 | -9.378881960928753 | -9.645546792637335 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Shares | 858.5627 | 859.4 | 856 | 864 | 860.5627 | 858.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 838.5627 | 859 | 859.5627 | 858 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | 862.5627 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Cash CHF | | | | | | | | | | 16088 | 15626 | 17336 | 11171 | | -31000 | -26244 | -27520 | -19200 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 17336 | -27000 | -19200 | -10681 | -1338 | -9207.0324 | -17296.9061472 | -25616.7950316336 | -34176.21362916728 | -42985.03032954392 | -52053.480858710194 | -61392.18231421835 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Gross Margin | 0.7740046838407494 | 0.7773296244784422 | 0.7801872504474735 | 0.7757401973859696 | 0.7411537931984029 | 0.736062950120032 | 0.7384189628203586 | 0.74 | 0.7880497758073455 | 0.7772620764239365 | 0.7797345249047181 | 0.6776366600875311 | 0.7547718596618797 | 0.746834370897387 | 0.7507289844205616 | 0.7409977791878173 | 0.7567786978405585 | 0.7537224930820925 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.7704289112253511 | 0.775763148216256 | 0.738567847706795 | 0.7787446143448509 | 0.7823553198068552 | 0.7281555502568661 | 0.7552030648042528 | 0.758 | 0.7605 | 0.7564129693635231 | | | | | | | | | 0.7848704627676902 | 0.759733125268706 | | ROIC | 0.05 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| M&D | 0.2855581576893052 | 0.289221140472879 | 0.2741979898113727 | 0.2862096559082422 | 0.2753683051080821 | 0.2892771405708189 | 0.2652508723378655 | 0.27613955212028163 | 0.2623809763716056 | 0.25450612833453495 | 0.24322074736058177 | 0.16197545696387197 | 0.19864570078167607 | 0.2032355058654131 | 0.1902441056402566 | 0.19463832487309646 | 0.1845267088813119 | 0.21706856414986603 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.3015038747794061 | 0.2874954027215888 | 0.2824334394688707 | 0.2740002446764637 | 0.2708378765155057 | 0.25664542132384005 | 0.19736134128231064 | 0.19104748462546628 | 0.20048176478045895 | 0.18925019397615855 | 0.2618464116719243 | 0.1686367015818726 | 0.16455136005646626 | 0.16249841921123978 | 0.158975657057158 | 0.1680111236814617 | 0.16212897338195845 | 0.14327935732103186 | 0.16050271762426488 | 0.1503797710227544 | | Mat | 0.01 | | Discount (3-1) | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| G&A | 0.33497267759562843 | 0.33977746870653686 | 0.3208040754509156 | 0.33428914377167246 | 0.3482720638854468 | 0.3576953854361163 | 0.33413548309469376 | 0.35242098296664276 | 0.0540077585772583 | 0.06624008651766403 | 0.0541902133438472 | 0.05217540547498498 | 0.04949100163606617 | 0.05264049464278152 | 0.040281596267599765 | 0.047906091370558374 | 0.035354765383990905 | 0.08797821408178504 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.3472723087546996 | 0.33751379183523356 | 0.3530587358580042 | 0.34502251241079884 | 0.33891166000207307 | 0.3232623832734083 | 0.05019047414071412 | 0.04385522734146587 | 0.060727718378903776 | 0.05506571677129623 | 0.07618888012618297 | 0.04906785378366823 | 0.04787915085752812 | 0.04728181113091359 | 0.04625680069920039 | 0.048885830744438225 | 0.04717431428258748 | 0.04168968255011264 | 0.046739708176877046 | 0.04240378337924555 | | Dis | 0.11 | | Long-term paper at 5.25-5.30%, 100bps above Tsys. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| R&D | 0.16963309914129587 | 0.1704450625869263 | 0.16060856395428885 | 0.18138170178714325 | 0.16253614209004544 | 0.18624966657775407 | 0.1539525929491036 | 0.18283130835135153 | 0.15431507884528187 | 0.15888608507570295 | 0.15924124939764314 | 0.2038101776366601 | 0.18664788220323578 | 0.20065218311946809 | 0.18820294926268433 | 0.2124048223350254 | 0.18148238350381554 | 0.24399349936311326 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.15852067827821684 | 0.17006252298639205 | 0.17458166790867827 | 0.1688361314456678 | 0.1700885404828648 | 0.16445100677776556 | 0.19036652820523858 | 0.19909265046879726 | 0.21184972319655157 | 0.19576309045167054 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.20837405483257035 | 0.218276779032181 | | NPV | 13928.006012798654 | | Management has excellent L-T track record, despite recent changes. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Operating Profit | 0.2211553473848556 | 0.20584144645340752 | 0.2547845243012529 | 0.21665777540677514 | 0.24280600302905136 | 0.21599093091491064 | 0.2630850679821923 | 0.22392567642135672 | 0.31734596201319965 | 0.2976297764960346 | 0.3760897183160293 | 0.31931691409937357 | 0.31998727504090163 | 0.2903061872697243 | 0.3320003332500208 | 0.28604854060913704 | 0.35541484007144014 | 0.20468221548732815 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.20037596869485153 | 0.21305627068775285 | 0.22918501456540885 | 0.2429030652968388 | 0.3357198924859066 | 0.3474085795417597 | 0.3172847211759895 | 0.30613973182780524 | 0.2818535266027131 | 0.31633396816439774 | -0.33803529179810726 | -0.21770455536554084 | -0.21243051091399437 | -0.20978023034215337 | -0.20523245775635837 | -0.21689695442589996 | -0.20930328766454592 | -0.1849690398711445 | 0.36925398213397803 | 0.34867279183452493 | | Share | 17.401241640521906 | | Biotech generics still don't have a toehold. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Profit Before Taxes | 0.1923497267759563 | 0.18463143254520167 | 0.23647253201156546 | 0.20892237930114696 | 0.22924411400247832 | 0.20905574819951986 | 0.26633377451570206 | 0.21662116376542248 | | | | | | | | 0.24175126903553298 | 0.3064620880012989 | 0.1577282909474239 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.23098438178172287 | 0.18826774549466715 | 0.2189892283720615 | 0.24071284416750166 | 0.27114359566035856 | 0.30398791565649136 | 0.32236403159503263 | 0.2725073092045569 | 0.23378269872797194 | 0.2794432296442595 | -0.3402336356466877 | -0.2275453339033775 | -0.23065235802031098 | -0.23669937352076836 | -0.240722513239512 | -0.2645479724393177 | -0.26554935001052543 | -0.24418560556188507 | 0.35958369768358966 | 0.3367143835289247 | | Return | -0.9374056056096334 | | Heavy reliance on 3 products with similar ASP profile. | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tax Rate | 0.26704545454545453 | 0.24896421845574387 | 0.2430858806404658 | 0.25853814235556977 | 0.24204204204204205 | 0.25486443381180224 | 0.24734583239213914 | 0.257 | 0.25301204819277107 | 0.24658897100625354 | 0.23280132085855806 | 0.22530864197530864 | 0.2557021159659247 | 0 | 0.2261760345059981 | 0.19553805774278216 | 0.23841059602649006 | 0.14480646059593427 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.2649132500765265 | 0.25766751318616915 | 0.2482598607888631 | 0.2518234270838995 | 0.272 | 0.28 | 0.2214581386032848 | 0.21235664076951535 | 0.2096890817064353 | 0.19697097181320994 | 0.24 | 0.24 | 0.24 | 0.23999999999999996 | 0.24 | 0.24 | 0.24 | 0.24 | 0.17137135227922945 | 0.14541757306346353 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Net Income | 0.12782982045277128 | 0.12291376912378303 | 0.1607462481068429 | 0.13510269405174713 | 0.1563747762632521 | 0.1380034675913577 | 0.17350499338226447 | 0.1330572899949157 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.17109793967322903 | 0.12522986392055904 | 0.14704288327349097 | 0.15265901938106788 | 0.16483039249577047 | 0.17561949193815188 | 0.2106192023760842 | 0.2 | 0.1800067616109538 | 0.21967506054407374 | -0.25857756309148267 | -0.17293445376656688 | -0.17529579209543633 | -0.17989152387578397 | -0.1829491100620291 | -0.20105645905388148 | -0.20181750600799933 | -0.18558106022703266 | 0.28422749172710593 | 0.27130141239789174 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Reported Net Income | 0.11280249804839969 | 0.11328233657858136 | 0.19454770755885997 | 0.10089357161909843 | 0.1871816053972188 | 0.09882635369431848 | 0.16827096618938756 | 0.13251987160344253 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -0.040346087028221136 | 0.11305627068775286 | 0.14230065713705034 | 0.15410220583112316 | 0.16469033218166365 | 0.17550225150897455 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Revenue y/y | - | - | 0.13395784543325528 | 0.042837273991655156 | - | - | 0.1442929918766349 | 0.07326700722467105 | 0.19414029599326188 | 0.17486367727248653 | 0.1500327472416747 | 0.050198269646719584 | -0.03605379594340041 | 0.013172573586200942 | 0.09098345755317205 | 0.06788633379917841 | 0.026243439140214875 | -0.09712087563451777 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.002352736144998202 | -0.0017546658159196538 | 0.06090958310774219 | 0.1108959690195388 | 0.09223680778927235 | 0.010866091403004097 | -0.06183550225397638 | -0.01830137854539693 | -0.08540273798153453 | -0.10322478659500478 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.0431213074503185 | | 0.2028656595081635 | 0.18388668299963395 | 0.09733355533883592 | 0.00715323087594566 | 0.06740847556119922 | -0.045750579695533866 | -0.10131851413599291 | -0.2844748536361713 | 0.5371976866456363 | 0.014578879863189398 | 0.0025072689730731845 | 0.011937538092936295 | -0.06324118880973639 | 0.02591787868038309 | 0.12024290623041511 | 0.1251229816540309 | 0.07677931519297698 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Revenue y/y LC | | | | | | | | | | | | | | | 0.1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.14 | | 0.09 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.174 | 0.102 | 0.059 | 0.1 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Pharma y/y LC | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.15 | | 0.1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.114 | 0.047 | 0.11 | -0.02 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Rituxan y/y LC | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.1 | 0.07 | 0.06 | 0.07 | 0.1 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Avastin y/y LC | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.02 | -0.06 | -0.09 | -0.1 | -0.02 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Herceptin y/y LC | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.05 | 0.08 | 0.12 | 0.04 | 0.14 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Diagnostics y/y | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.06893792157311074 | 0.032727272727272716 | 0.041321458160729074 | 0.035803083043262074 | -0.06509841574651942 | -1 | #ERROR_#DIV/0! | #ERROR_#DIV/0! | #ERROR_#DIV/0! | #ERROR_#DIV/0! | #ERROR_#DIV/0! | 0.06623064823246949 | 0.005512850376582001 | 0.06494208494208498 | 0.2877963889493147 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Diagnostic y/y LC | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.1 | | 0.09 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.056 | 0.105 | 0.09 | 0.08 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| M&D y/y | - | - | 0.0888463641334063 | 0.03197884106756432 | - | - | 0.10224999999999995 | 0.061689216876127606 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -0.0053441913729481705 | | 0.1402014871671864 | 0.1418954454612391 | -0.14084377302873985 | 0.10866670124251376 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| G&A y/y | - | - | 0.08599394080633882 | 0.025992632009824046 | - | - | 0.09784542399683738 | 0.058237668615354954 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.013809102960671726 | | 0.10743405275779372 | 0.10090948462537885 | -0.035011801730920555 | 0.11175549765689508 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| R&D y/y | - | - | 0.07363092498849522 | 0.1097511219910241 | - | - | 0.08386277001270659 | 0.050101322750746524 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.11907066795740562 | | 0.10690725649980592 | 0.15495179666958814 | 0.2725755046289271 | 0.11157806678724591 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Operating Profit | - | - | 0.3063889869396399 | 0.09763513513513522 | - | - | 0.23986390700311877 | 0.10487106107533983 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.10913268236645601 | | 0.28534820196558813 | | | -0.08017720097335745 | 0.029914529914529808 | -0.12145162352631234 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Income from Assoc. Companies | - | - | 0.5 | -0.3846153846153846 | - | - | | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.18918918918918926 | | -0.627906976744186 | 0 | 0 | 0 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Net Financial Income | - | - | -0.31908831908831914 | -0.6415770609318996 | - | - | - | -0.5843207825765969 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -1.754636617171253 | | -0.7708425618309341 | -0.7436149648631798 | -2.1573365350255624 | 1.8537461678109746 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Profit Before Taxes | - | - | 0.3940746753246753 | 0.18003766478342742 | - | - | 0.3294294294294293 | 0.1330722909730102 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -0.1497862525757121 | | 0.2770664375861349 | 0.2896293957283107 | 0.3393517979174818 | 0.22525526811705765 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Minority Interests | - | - | 0.477088948787062 | 0.25667351129363447 | - | - | 0.6946564885496183 | -0.10639136046998865 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -13.617647058823529 | | 0.7593938510877385 | 0.3566858355665701 | 0.5843113747061166 | 0.2944970936953366 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Net Income | - | - | 0.4259541984732824 | 0.14625176803394635 | - | - | 0.2696456086286594 | 0.14267721422019086 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -0.2365195066981972 | | 0.2061892088752839 | 0.23617416138624936 | 0.2728379635362823 | 0.19103888723838436 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Net Income After Exceptionals | - | - | 0.9557093425605536 | -0.0712093308778392 | - | - | 0.028687017285766725 | 0.15407772178764811 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -3.9229948572900177 | | 0.25816885401752154 | 0.22355666613924408 | 0.27306999762332884 | 0.19116650657623802 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| EPS | - | - | 0.430223232146679 | 0.140149038713395 | - | - | 0.2734378240147115 | 0.14267721422019086 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -0.2546842097083917 | | 0.2083860758644558 | 0.23617416138624936 | 0.2728379635362823 | -0.1353596041703481 | 0.013590844062947083 | -0.14114326040931557 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Shares | - | - | | | - | - | 0.3064311565815556 | 0.17124789823043063 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.24010160092268173 | 0.22959823690009884 | 0.2600643067357822 | 0.18389813893782847 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Reported Diluted EPS After Exceptionals | - | - | 0.9449298542036897 | -0.08025713289230896 | - | - | 0.026696798876403083 | 0.15339148720865947 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | -3.885011675710488 | | 0.25609102568827624 | 0.22332428171071594 | 0.2728379635362823 | 0.19103888723838436 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| WW Y/Y Growth | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Rituxan | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.1879795396419437 | 0.20546318289786214 | 0.20113636363636367 | 0.31922196796338675 | 0.23358449946178683 | 0.18423645320197046 | 0.11352885525070966 | 0.1396357328707718 | 0.14223385689354284 | 0.16056572379367728 | 0.1724723874256584 | 0.08980213089802125 | 0.07486631016042788 | 0.04659498207885315 | 0.06666666666666665 | 0.1061452513966481 | 0.05259417199715699 | 0.10753424657534238 | 0.024456521739130377 | -0.06502525252525249 | 0.08440243079000664 | 0.04823747680890533 | 0.007957559681697646 | 0.036461850101283 | -0.031133250311332517 | -0.11504424778761058 | -0.10460526315789476 | 0.034527687296416865 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Herceptin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.19207317073170738 | 0.2921348314606742 | 0.5844504021447721 | 0.8638753598471653 | 1.2020460358056266 | 1.0695652173913044 | 0.7072758037225042 | 0.5696022727272727 | 0.3565621370499419 | 0.27521008403361336 | 0.19821605550049548 | 0.14117647058823524 | 0.048801369863013644 | 0.02883031301482708 | 0.07113316790736146 | 0.04916732751784303 | 0.066938775510204 | 0.07125700560448367 | 0.024710424710424617 | -0.02191987906273618 | 0.08416220351951043 | 0.03811659192825112 | 0.02260738507912574 | -0.021638330757341562 | -0.02187720536344384 | -0.042476601871850206 | -0.12380250552689753 | 0.06477093206951023 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Avastin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 4.416666666666667 | 1.0532544378698225 | 1.0680851063829788 | 1.403361344537815 | 1.6 | 1.0547550432276656 | 0.5246913580246915 | 0.4545454545454546 | 0.3653846153846154 | 0.38288920056100983 | 0.4331983805668016 | 0.3641826923076923 | 0.22535211267605626 | 0.23732251521298164 | 0.27212806026365355 | 0.32599118942731287 | 0.312997347480106 | 0.31557377049180335 | 0.17986676535899337 | 0.0219269102990034 | 0.12188552188552193 | 0.07601246105919013 | 0.008782936010037545 | -0.05071521456436934 | -0.1494597839135654 | -0.2420382165605095 | -0.24378109452736318 | -0.07534246575342463 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| NeoRecormon/Epogin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.05521472392638027 | 0.07344632768361592 | 0.06818181818181812 | 0.12734082397003754 | 0.036821705426356655 | -0.00877192982456143 | -0.0514184397163121 | -0.01661129568106312 | -0.024299065420560706 | -0.03716814159292037 | -0.03177570093457949 | -0.1385135135135135 | -0.15325670498084287 | -0.17279411764705888 | -0.17567567567567566 | -0.10784313725490191 | -0.14479638009049778 | -0.08666666666666667 | -0.08430913348946134 | -0.1648351648351648 | -0.10317460317460314 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tamiflu | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 2.925925925925926 | 7.210526315789474 | 1.5363636363636362 | 6.516129032258065 | 0.4174528301886793 | 1.3076923076923075 | 1.3978494623655915 | 0.4263233190271818 | 0.4392678868552413 | 0.25277777777777777 | -0.6158445440956652 | -0.4864593781344032 | -0.6786127167630058 | -0.8913525498891353 | -0.6070038910505837 | -0.646484375 | 0.44244604316546754 | 11.428571428571429 | 8.841584158415841 | 5.607734806629834 | 0.28927680798004984 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| CellCept | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.0027100271002709064 | 0.22857142857142865 | 0.3086053412462908 | 0.33717579250720453 | 0.22702702702702693 | 0.016279069767441756 | 0.05668934240362811 | 0.04525862068965525 | 0.048458149779735615 | 0.15102974828375282 | 0.04077253218884125 | 0.12989690721649483 | 0.02310924369747891 | 0.03976143141153088 | 0.057731958762886615 | 0.051094890510948954 | 0.06160164271047219 | -0.2160611854684512 | -0.2943469785575049 | -0.5017361111111112 | -0.30947775628626695 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Pegasys | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.12456747404844282 | 0.20338983050847448 | 0.18243243243243246 | 0.24749163879598668 | 0.07692307692307687 | 0.05352112676056331 | 0 | 0.0536193029490617 | 0.1428571428571428 | 0.08823529411764697 | 0.0942857142857143 | 0.13740458015267176 | -0.07750000000000001 | 0.02211302211302213 | 0.05744125326370764 | -0.004474272930648726 | 0.06504065040650397 | 0.07932692307692313 | 0.08148148148148149 | -0.1573033707865169 | 0.12213740458015265 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xeloda | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.4347826086956521 | 0.484375 | 0.46896551724137936 | 0.5616438356164384 | 0.4424242424242424 | 0.2315789473684211 | 0.1220657276995305 | 0.14035087719298245 | 0.12184873949579833 | 0.20512820512820507 | 0.21338912133891208 | 0.19999999999999996 | 0.05243445692883886 | 0.03546099290780136 | 0.05862068965517242 | 0.0608974358974359 | 0.053380782918149405 | 0.13013698630136994 | 0.061889250814332275 | -0.06948640483383683 | 0.18918918918918926 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Tarceva | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 7.294117647058824 | 2.017543859649123 | 1.2159090909090908 | 1.0891089108910892 | 0.6666666666666667 | 0.41279069767441867 | 0.33333333333333326 | 0.28436018957345977 | 0.225531914893617 | 0.17695473251028804 | 0.1576923076923078 | 0.09963099630996308 | 0.14583333333333326 | 0.11888111888111896 | 0.07308970099667778 | 0.07046979865771807 | 0.036363636363636376 | 0.018750000000000044 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Lucentis | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.24479166666666674 | -0.1648351648351648 | -0.18250950570342206 | -0.13793103448275867 | 0.029288702928870203 | 0.20175438596491224 | 0.29767441860465116 | 0.30666666666666664 | 0.2032520325203253 | 0.2007299270072993 | 0.17204301075268824 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Bonviva/Boniva | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 3.3809523809523814 | 9.142857142857142 | 2.5098039215686274 | 1.2666666666666666 | 1.2173913043478262 | 0.619718309859155 | 0.5810055865921788 | 0.4176470588235295 | 0.303921568627451 | 0.16521739130434776 | 0.1766784452296819 | 0.03319502074688807 | 0.03759398496240607 | -0.04850746268656714 | -0.16516516516516522 | 0.11244979919678721 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xenical | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.006849315068493178 | 0 | 0.11724137931034484 | 0.17518248175182483 | 0.23129251700680276 | 0.10303030303030303 | -0.012345679012345734 | 0.05590062111801242 | -0.09944751381215466 | -0.03296703296703296 | -0.05625000000000002 | -0.16470588235294115 | -0.16564417177914115 | -0.2727272727272727 | -0.16556291390728473 | -0.21126760563380287 | -0.24264705882352944 | -0.171875 | -0.2222222222222222 | -0.1964285714285714 | -0.11650485436893199 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Xolair | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 1.1315789473684212 | 0.8181818181818181 | 0.5294117647058822 | 0.6849315068493151 | 0.5308641975308641 | 0.33000000000000007 | 0.29807692307692313 | 0.17886178861788626 | 0.09677419354838701 | 0.11278195488721798 | 0.07407407407407418 | -0.0482758620689655 | -0.08088235294117652 | -0.09459459459459463 | 0 | 0.13043478260869557 | 0.21599999999999997 | 0.20149253731343286 | 0.08275862068965512 | -0.038461538461538436 | -0.02631578947368418 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Valcyte/Cymeve | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0 | 0.25316455696202533 | 0.23456790123456783 | 0.31325301204819267 | 0.2790697674418605 | 0.14141414141414144 | 0.26 | 0.27522935779816504 | 0.1272727272727272 | 0.21238938053097356 | 0.08730158730158721 | 0.03597122302158273 | 0.032258064516129004 | -0.007299270072992692 | 0.04379562043795615 | 0.03472222222222232 | 0.0234375 | 0.05147058823529416 | 0.034965034965035 | -0.046979865771812124 | 0.13740458015267176 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Nutropin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.00917431192660545 | 0.051724137931034475 | 0.05454545454545445 | 0.12280701754385959 | 0.07272727272727275 | 0.032786885245901676 | 0.01724137931034475 | 0.03125 | -0.008474576271186418 | -0.031746031746031744 | 0 | -0.14393939393939392 | -0.1709401709401709 | -0.19672131147540983 | -0.10169491525423724 | -0.008849557522123908 | 0.07216494845360821 | 0.09183673469387754 | -0.05660377358490565 | -0.2053571428571429 | -0.125 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Pulmozyme | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 0.059523809523809534 | 0.1858663639710394 | 0.16279069767441867 | 0.2441860465116279 | 0.2247191011235956 | 0.061855670103092786 | 0.08000000000000007 | 0.08411214953271018 | 0.0183486238532109 | 0.16504854368932032 | 0.14814814814814814 | 0.10344827586206895 | 0.054054054054053946 | 0 | -0.032258064516129004 | 0.0859375 | 0.02564102564102555 | 0.06666666666666665 | 0.04166666666666674 | -0.07913669064748197 | 0.125 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Rocephin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Neutrogin | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Activase/TNKase | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Model NI | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 9786 | 9919 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| CFFO | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 12177 | 16877 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| P&E | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 3139 | 2984 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| FCF | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 9038 | 13893 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Headcount | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | 82089 | 85080 | 88509 | 91747 | 94052 | 93734 | 94442 | 97735 | 101465 | 100920 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| Cash | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |