ABC
1Main
2Brand NameAlimta
3Generic Namepemetrexed
4IP4/25/2008 Paragraph IV was filed. Teva was sued 6/10/2008. Trial date 11/8/2010, 30-month stay expires 10/24/2010. 5,344,932 composition of matter.
5Clinical Trials
6p3 studies in gastric and colorectal cancer to begin in 2005
7Alimta to replace Taxotere in 2nd line NSCLC
8More convenient administration and better tolerability (less neutropenia), medicare pricing helps too
9
10
11
12Phase III "CRA8000" Maintenance NSCLC study - ASCO 2009
13Pemetrexed 13.4 months vs 10.6 for placebo. Squamous had negative outcome.
14http://meeting.ascopubs.org/cgi/content/short/27/18S/CRA8000