A	B	C
1	Main
2		Brand Name	Byetta
3		Generic Name	exenatide
4		Economics	Profit-share with Amylin. Ex-US royalties to Amylin.
5		Competition	Insulin (+ does not require glucose monitoring and provides weight loss)
6		Manufacturing	Manufacturing straightford, product is just an amino acid sequence and not a biologic. Efficacy achieved with microgram dosing
7		Administration	current pen device to deliver either 5mg or 10mg twice a day for 30 months --figure out how painful/large this pen device is.
8		Clinical Trials
9			recently announced lt-data continued positive data at 82 weeks
10			positive data on restoration of First-Phase insulin response (unclear whether this can get added to the label)
11
12
13
14			Phase III LAR formulation n=300
15			LLY maintains this trial is enough to garner approval--LLY comments to Cowen 2008