| A | B | C | |
|---|---|---|---|
| 1 | Main | ||
| 2 | Brand Name | Tabrecta, fka INCB28060 | |
| 3 | Indication | Solid tumors | |
| 4 | Mechanism | c-MET inhibitor | |
| 5 | V617F mutation is acquired in MF patients. | ||
| 6 | Administration | Oral | |
| 7 | Economics | NVS | |
| 8 | IP | ||
| 9 | Clinical Trials | ||
| 10 | Phase II "GEOMETRY mono-1" | ||
| 11 | 52% ORR in 2L, 44% ITT | ||
| 12 | |||
| 13 | Phase 1, n = 40 | ||
| 14 | Dose escalation. | ||
| 15 | Data expected Q1 2012 | ||
| 16 | Per 10-k, compnay expects to transtion this drug to NVS once done. |