A	B	C
1	Main
2		Brand Name	Cervarix
3		Mechanism	Gardasil protects against genital warts, whereas Cervarix does not.
4		Competition	MRK's Gardasil received strong recommendation from ACIP
5		Timeline	Filed in EU in March 2006. Gardasil filed in EU in December 2005.
6			Approved in the US 10/16/2009, versus Gardasil in 10/2006. Suffered approvable letter 12/2007. Filed 4/2007.
7			Approved in Japan 10/16/2009, ahead of Gardasil.
8		Clinical Trials
9			Phase III 008 "PATRICIA" study n=18,644 published in Lancet.
10			Interim analysis showed 79.5% coverage against persistent infections?
11			92% versus 51.9% CIN2+ with HPV31, 33 and 45. 100% in ATP-E (all three doses).
12
13			Head-to-Head vs Gardasil
14			n=1042, data expected in 2008