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| Main | | |
| Brand Name | Promacta (US), Revolade (EU) |
| Generic Name | eltrombopag |
| Indication | ITP |
| Mechanism | oral platelet growth factor |
| Competition | Nplate (AMG531, Amgen). May have more durable responses than Nplate. |
| Approval | 10/10 Japan approval. |
| | 3/12/10 EU approval. |
| | 12/18/09 EMEA positive opinion. |
| Clinical Trials | p2 data 6/19/06 shows 81% of patients achieving primary endpoint (>50k/micro liter after up to 6wks) vs 11% for placebo after "up to 6 weeks" of dosing |
| | data presented at EHA |
| | ASCO 2006 |
| | oral platelet growth factor increases platelet counts in thrombocytopenic patients and healthy subjects |