A	B	C	D	E	F	G	H	I	J	K	L	M
1	Main
2		Brand Name	Concerta Extended-Release
3		Generic Name	methylphenidate extended-release
4		Label	http://www.concerta.net/concerta/assets/prescribing_info.pdf#zoom=56
5		Indication	ADHD
6		Mechanism	Stimulant blocks the reuptake of dopamine and norepinephrine. Same mechanism as Ritalin.
7		Approved	April 2000 approval.
8		Competition	Adderall (generic), Adderall XR (Shire), Vyvanse (Shire), Ritalin (generic), Strattera (Lilly), Daytrana.
9		IP	IPXL and ADRX suing. CP holding up generics? OROS patents are orange-book listed and expire in 2017-2018.
10			JNJ filed Citizen Petition 3/19/2004.
11			http://www.fda.gov/ohrms/DOCKETS/
12		Economics	1
13		Clinical Studies
14			3 Phase III ADHD Trials - Children vs Placebo. N=416 (3 studies)
15			Study 1 - Approx 7 vs 11.5 symptoms Concerta vs Placebo. N=122
16			Study 2 - Approx 5 vs 10.5 "
17			Study 3 - Approx 6 vs 10 "
18
19
20		Rx		TRx	NRx
21			6/1/2007	132809	132496
22			5/25/2007	158528	158166
23			6/1/2006	130823	130410
24
25
26			2000	2001	2002	2003	2004	2005	2006	2007	2008	2009	2010
27		US				#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!
28		ROW				#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!
29		WW				#ERROR_#REF!	#ERROR_#REF!	774	929	1027	1142.5