A	B	C	D	E	F	G	H	I	J	K	L	M	N	O	P	Q	R	S	T	U	V	W	X	Y	Z	AA	AB	AC	AD	AE
1	Main
2		Biosense Webster - CARTO 3 magnetic navigation/mapping for catheters in electrophysiology (arrythmias, AF ablation). CARTO EXPRESS.
3		Irrigated Catheter platform - ThermoCool Catheter technology. Contact force catheter allows physicians to see pressure amounts.
4		OCTARAY Mapping Catheter with TRUEref technology (CARTO 3 Version 7 System)
5
6		Nevo sirolimus-eluting stent: RES technology allows for a number of reservoirs for polymer and drug. Submit Q1 2010 for CE Mark. Thin strut CoCr stent scaffold. Superior to TAXUS Liberte. NEVO2 versus Xience data will be available in 2011, 2012 PMA submission.
7		Cypher, Cypher Select Plus, Cypher Stent 225: Shelf life has hurt.
8		Endovascular - "STROLL" Study enrollment completed in Q1 2010, indication in 2011. PTA Balloon portfolio (014 and 035 balloons).
9		AAA device.
10		Exoseal - vascular closure device area, submission in Q1 2010 for CE Mark and FDA, extravascular bio-reabsorbable product. Launched in US 5/27/2010.
11
12			2002	2003	2004	2005	2006	2007	2008	2009	2010
13		EU Coronary Stents
14		EU Cordis ex Coronary Stents	344.5	524	654.2
15		EU Total Cordis	155	0	0
16		WW Coronary Stents				2602	2905	2599	1864	1420	1283
17		WW Cordis ex Coronary Stents	738.8	1120	1301.3000000000002
18		WW Total								2700
19
20		PTCA procedures					#REF!
21		Pricing					#ERROR!
22		DES ASP				2351	2245	2151	1875	1719	1619
23
24		2000 - JNJ wins damages against BSX and MDT for $324m and $271m and wins retrials but still faces appeal
25		Ding patent - held by BSX - upheld twice - covers the use of polymer/drug combination
26		Palmaz-Schatz, Gray - JNJ wins in May 2006
27		Jang - BSX wins in May 2006
28
29		JNJ looking to prevent the launch of Taxus Liberte
30		BSX liability to JNJ 500m-1B as a result of Palmaz (expired 11/2005)
31
32		6/12/2006: Largest Independent US DES Registry Shows Excellent Outcomes for TAXUS Stent System in Diabetics
33			Analysis on data on diabetic patients revealed numerically favorable outcomes for TAXUS Express compared to Cypher in reducing MACE.
34			Follow-up on 5,566 at 8 coronary centers, including 1,680 diabetics.
35			TAXUS patients had more complex lesions but 6.8% MACE vs 7.1% for Cypher. Death 1.9% vs 3.4% for Cypher p=NS.
36
37		Q106: 14.7% operational growth driven by CYPHER worldwide. Biosense Webster also had double-digit growth.
38		6/28/06 Signs agreement with ClearStream to distribute PTCA balloon catheter CRESCENDO.
39
40		MDT - Endeavor delivery weak - lack of a Rapid Exchange system. Positive clinical data - EU before US. Zero incidence of LST while Cypher has 0.6% and Taxus 0.7%.
41		ABT/GDT will market both Xience and Zomaxx? Different stents and different coating. Bear says 28% share by 2010. Xience little better than Zomaxx? Unclear.
42		DES pricing has been firm in 2006 according to JNJ and BSX - 7/1/06 - BSX mgmt comments DES pricing/penetration and share little changed
43
44		Cypher Select Plus - hydrophilic coating - 3rd-gen product - launch in EU in September
45		Competition includes Xience V and Endeavor
46		9/26/2006 - Cordis Endovascular receives approval to market PRECISE Nitinol Stent and ANGIOGUARD Emboli Capture Guidewire to treat clogged neck arteries, (carotid artery disease)
47		5/2007 - CoSTAR stent fails.
48		Q208: Xience to launch.
49
50		POTECT - n=8800 ENDEAVOR vs CYPHER
51
52
53
54		1995	1996	1997	1998	1999	2000	2001	2002	2003	2004	2005	2006	2007	2008	2009
55	Cordis
56	Stents - Coronary	450	700	600	207	201	240	444	610	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	2680.853686494346	1750.9916706694423	1618		0.5555555555555556	-0.14285714285714285	-0.655	-0.028985507246376812	0.19402985074626866	0.85	0.3738738738738739	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	-0.34685295229254015	-0.07595220062845685
57	U.S.	255	510	460	102	79	140	314	370	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	1494.3634471151063	1705.8536864943464	930.9916706694423	818		1	-0.09803921568627451	-0.7782608695652173	-0.22549019607843138	0.7721518987341772	1.2428571428571429	0.17834394904458598	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	0.14152530282209835	-0.45423709076556384	-0.12136700491444152
58	International	195	190	140	105	122	100	130	240	370	694	#ERROR_#REF!	#ERROR_#REF!	975	820	800		-0.02564102564102564	-0.2631578947368421	-0.25	0.1619047619047619	-0.18032786885245902	0.3	0.8461538461538461	0.5416666666666666	0.8756756756756757	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	-0.15897435897435896	-0.024390243902439025
59	Stents - Peripheral	85	110	131	139	180	232	300	383	465	548	632	790	915	1055	1175		0.29411764705882354	0.19090909090909092	0.061068702290076333	0.2949640287769784	0.28888888888888886	0.29310344827586204	0.27666666666666667	0.21409921671018275	0.17849462365591398	0.15328467153284672	0.25	0.15822784810126583	0.15300546448087432	0.11374407582938388
60	U.S.	50	70	86	89	100	132	175	223	265	310	357	470	545	625	675		0.4	0.22857142857142856	0.03488372093023256	0.12359550561797752	0.32	0.32575757575757575	0.2742857142857143	0.18834080717488788	0.16981132075471697	0.15161290322580645	0.3165266106442577	0.1595744680851064	0.14678899082568808	0.08
61	International	35	40	45	50	80	100	125	160	200	238	275	320	370	430	500		0.14285714285714285	0.125	0.1111111111111111	0.6	0.25	0.25	0.28	0.25	0.19	0.15546218487394958	0.16363636363636364	0.15625	0.16216216216216217	0.16279069767441862
62	PTCA, Angiography	0	562	609	553	533	549	536	559	580	601	635	692	737.24	774.9744000000001	814.372864			0.08362989323843416	-0.09195402298850575	-0.03616636528028933	0.0300187617260788	-0.023679417122040074	0.04291044776119403	0.03756708407871199	0.03620689655172414	0.056572379367720464	0.08976377952755905	0.06537572254335261	0.05118333242905981	0.050838407049316706
63	U.S.		272	286	250	227	248	243	259	249	244	235	260	275	285	295			0.051470588235294115	-0.1258741258741259	-0.092	0.09251101321585903	-0.020161290322580645	0.06584362139917696	-0.03861003861003861	-0.020080321285140562	-0.036885245901639344	0.10638297872340426	0.057692307692307696	0.03636363636363636	0.03508771929824561
64	International		290	323	303	306	301	293	300	331	357	400	432	462.24	489.97440000000006	519.372864			0.11379310344827587	-0.06191950464396285	0.009900990099009901	-0.016339869281045753	-0.026578073089700997	0.023890784982935155	0.10333333333333333	0.07854984894259819	0.12044817927170869	0.08	0.07	0.06	0.06
65	Biosense (Noga, DMR)				7.6	21.3	34.5	63.9	88.668	115.9866	139.18392	162.937008	187.37755919999998	215.48419307999995	247.80682204199994	284.97784534829987					1.8026315789473686	0.6197183098591549	0.8521739130434782	0.38760563380281704	0.3080998781973202	0.20000000000000004	0.1706597141393919	0.14999999999999994	0.14999999999999988	0.14999999999999994	0.14999999999999974
66	U.S.				2.6	11	20.5	41.4	56.718	68.0616	81.67392	93.92500799999999	108.01375919999998	124.21582307999996	142.84819654199995	164.27542602329993					3.230769230769231	0.8636363636363636	1.0195121951219512	0.37	0.2	0.2	0.15	0.15	0.15	0.15	0.15
67	International				5	10.3	14	22.5	31.95	47.925	57.51	69.012	79.3638	91.26836999999999	104.95862549999998	120.70241932499997					1.06	0.3592233009708737	0.6071428571428571	0.42	0.5	0.2	0.2	0.15	0.15	0.15	0.15
68	Total Cordis	535	1372	1340	906.6	935.3	1055.5	1343.9	1640.6680000000001	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	4548.577879574346	3828.772892711442	3892.3507093483		1.5644859813084113	-0.023323615160349854	-0.3234328358208955	0.03165673946613714	0.12851491500053464	0.2732354334438655	0.2208259543120768	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	-0.1582483593597969	0.016605272346627353
69	U.S.	305	852	832	443.6	417	540.5	773.4	908.718	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	2332.3772063151064	2650.0695095743463	1983.8398672114422	1952.2754260233		1.7934426229508196	-0.023474178403755867	-0.46682692307692303	-0.059963931469792654	0.2961630695443645	0.4308973172987974	0.17496508921644685	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	0.1362096587117476	-0.2514008179619084	-0.01591078075898852
70	International	230	520	508	463	518.3	515	570.5	731.95	948.925	1346.51	#ERROR_#REF!	#ERROR_#REF!	1898.50837	1844.9330255	1940.0752833249999		1.2608695652173914	-0.023076923076923078	-0.08858267716535433	0.11943844492440595	-0.006366968936909039	0.10776699029126213	0.28299737072743214	0.29643418266275007	0.4189846405142662	#ERROR_#REF!	#ERROR_#REF!	#ERROR_#REF!	-0.02821970413541028	0.05156949141783353